<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL26432 99169 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDI+ IDV+ RTV 17
2 AZT+ DDI+ NVP 66

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y188C   V35T, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, Q207K, R211S, H221HY, L228LR, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V  
>99169| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLCVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKYQKEPPFRWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, L19I, K20I, E35D, M36I, R41K, C67S, H69K, V77I, V82I, L89M  
>99169| codons 1-99
PQITLWQRPLVTVKIGGQIIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGKKAIGTVLIGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005