Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL26432 | 99169 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ IDV+ RTV | 17 |
| 2 | AZT+ DDI+ NVP | 66 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y188C | V35T, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, Q207K, R211S, H221HY, L228LR, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V |
| >99169| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYMDDLCVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKYQKEPPFRWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19I, K20I, E35D, M36I, R41K, C67S, H69K, V77I, V82I, L89M |
| >99169| codons 1-99 PQITLWQRPLVTVKIGGQIIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEISGKKAIGTVLIGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |