Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL24653 | 89420 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 91 |
| 2 | D4T+ DDI+ ABC | 87 |
| 3 | 3TC+ TDF+ EFV | 35 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E40D, K43KR, V60I, A98S, K122E, D123S, I135T, K173IV, Q174K, D177E, T200AE, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291ED, V292I, I293IV, E297A, D324E, I329V |
| >89420| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPEIVI YQYMDDLYVGSDLEIGQHREKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, L19LP, K20I, E35D, M36I, R41K, H69K, K70KR, V82I, L89M |
| >89420| codons 1-99 PQITLWQRPLVTVRIGGQPIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |