Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL21333 | 84771 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ IDV | 78 |
| 2 | D4T+ 3TC+ EFV | 82 |
| 3 | D4T+ DDI+ EFV | 117 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | K103KN, Y188L | K20R, V35T, V60I, S68G, A98S, V106VI, K122E, D123S, K126KR, I135T, K173I, Q174K, D177EG, V179VM, T200A, I202V, Q207K, R211NS, F214L, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329V |
| >84771| codons 1-332 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSITVLDVGDAYFSVPL DESFRRYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPGIMI YQYMDDLLVGSDLEIGQHRAKVEELRKHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE MELAENREILKEPVHGVYYDPSKELIAEVQKQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L89V | I13V, K14R, K20I, E35D, M36I, R41K, L63LP, H69K, A71T |
| >84771| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKTIGTVLVGPTPVNIIGRNVLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |