Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL14814 | 77297 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 47 |
| 2 | AZT+ 3TC+ NFV | 161 |
| 3 | D4T+ DDI+ 3TC+ NFV | 60 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | K20R, K32I, V35T, T39K, K43E, K49R, V118I, K122E, D123NS, I135V, E169A, K173A, Q174K, D177E, I178M, T200A, E203D, Q207E, H208Y, R211K, V245Q, E248D, A272P, E291D, V292I, I293V, E297A, D324E, I329V |
| >77297| codons 1-333 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIIALTEICKELEEEGKISRIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILAPFRAKNPEMVI YQYVDDLYVGSDLEIGQHRAKIDELREYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | I13V, K14R, K20I, E35D, M36V, R41K, Q61H, I62V, L63P, C67E, H69K, A71I, T74S, V82I, L89I, I93M |
| >77297| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDVNLPGKWKPKIIGGIGGFIKVRQYD HVPIEIEGKKIIGSVLVGPTPINIIGRNIMTQMGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |