Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL14482 | 74644 | Portugal | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ EFV | 261 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V | K103N | K238KT | V35T, E36A, T39E, S48T, K49KR, K122E, D123N, I135T, A158S, S163ST, E169A, K173A, Q174K, D177E, T200A, Q207K, R211ST, V245Q, P247T, E248D, D250E, A272P, K277KR, E291D, V292I, I293V |
| >74644| codons 1-311 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITRIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQSTMTKILAPFRAKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLTWGFTTPDKKHQKEPPFLWMGYELHPDTWT VQPIQLTDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| Q2H, L19T, M36I, R41K, H69K, L89M, I93L |
| >74644| codons 1-99 PHITLWQRPLVTIKIGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |