Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL1184 | 81963 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI | 248 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, T215Y | K219R | K20KR, V35T, T39E, K43R, E44D, V60I, W88C, A98S, L109I, V118I, K122E, D123S, I135LV, T139TI, S162SDGN, Q174K, D177E, I195K, T200A, E203EK, L210S, R211D, D218E, K223Q, L228R, V245Q, E248A, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329V |
| >81963| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEELERDGKISKIGPENPYNTPI FAIKKKDSDKWRKLVDFRELNKRTQDFCEVQLGIPHPSGLKKKKSVTVIDVGDAYFSIPL DESFRKYTAFTIPSVNNEIPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKKNPEIVI YQYMDDLYVGSDLEKGQHRAKIKELRQHLSDWGFYTPERKHQQEPPFRWMGYELHPDKWT VQPIQLPAKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE MELAENREILKEPVHGVYYEPSKELIAEVQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M |
| >81963| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |