Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL11415 | 63407 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 104 |
| 2 | DDI+ 3TC+ IDV | 82 |
| 3 | DDI+ 3TC+ IDV+ AZT+ EFV | 4 |
| 4 | AZT+ 3TC+ EFV | 106 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | K20R, E28K, V35T, E40D, K43R, V60I, A98S, K101KQ, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248EDKN, D250E, A272P, T286A, E291D, V292I, I293IV, E297A, D320E, D324E, I329V, Q334IL |
| >63407| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTKEKIKALTEICTDMEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLQKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQGLG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, R41K, C67S, H69K, V82I, L89M |
| >63407| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVRQYD QILIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |