Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL10877 | 59219 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 65 |
| 2 | D4T+ DDI+ IDV | 161 |
| 3 | AZT+ DDI+ IDV+ SQV | 33 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, L90M | L10LI, I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63LP, H69K, A71V, T74S, L89I, T91TN | T96TN |
| >59219| codons 1-99 PQITLWQRPIVTVRVGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGKKVIGSVLVGPTPTNIIGRNIMNQIGCNLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | E28A, V35T, K43Q, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, T200A, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E |
| >59219| codons 22-324 KQWPLTAEKIKALTEICTELEQEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELN KRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPG IRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVIYQYMDDLYVGSDLEIGQHRAK IEELRKHLWNWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIQLPDKESWTVNDIQKLV GKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAELELAENREILKEPVHGVYYDP SKE |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |