Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL10146 | 83346 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ IDV+ RTV | 151 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T | I13V, K14R, K20I, E35D, M36I, N37ND, R41K, I62V, I66F, H69K, L89M |
| >83346| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDIDLPGKWKPKIIGGIGGFVKVRQYD QVLIEFCGKKAIGTVLVGPTPTNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y188L | V179E | V35T, V60I, A98S, K122E, D123S, I135T, T139I, E169EG, K173I, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, E297AV |
| >83346| codons 1-313 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNEIPGIRYQYNVLPQGWKGSPAIFQSSMTKILGPFRIKNPEIEI YQYMDDLLVGSDLEIGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVPLTVEAE LELAENREILKEP |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |