Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL28285 | 65163 | Portugal | 2002 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ TDF+ D4T | NA |
| 2 | ATV+ IDV+ DDC+ AZT | NA |
| 3 | Unknown | 37 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62V, D67DG, V75I, F116Y, K219KE | Y181C | K11Q, A33V, V35T, E36D, K49R, V60I, S68G, D121H, K122E, D123S, I135V, S162AD, I167IV, K173T, Q174R, D177E, T200A, I202V, Q207E, R211K, F214FL, V245K, A272P, K277R, T286A, A288T, E291D, V292I, I293V, P294T, S322T, I326V |
| >65163| codons 1-333 PISPIETVPVQLKPGMDGPKVKQWPLTEEKIKVLTDICTEMEKEGKISRIGPENPYNTPI FVIKKKGGTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL HESFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQDSMTKVLEPFRTRNPEIVI CQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKTLTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82VA, I84IV, L90M | L33F, K43KT, L89V | L10V, I13V, K14R, G16E, K20IM, E35G, M36I, R41K, Q61H, C67Y, G68GE, H69Q, I72R |
| >65163| codons 1-99 PQITLWQRPVVTVRIEGQLMEALLDTGADDTVFEGINLPGKWTPKMIGGIGGFIKVRQYD HILIEIYEQKARGTVLVGPTPANVIGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |