Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL16925 | 71340 | Portugal | 2002 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ DDI | NA |
| 2 | Unknown | 61 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | L33LI, L89V | L10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PA |
| >71340| codons 1-99 PQITLWQRPVVTARIGGQLVEVLLDTGADDTVIEGINLPGKWKPKIIGGIGGFIRVRQYD QIPIEVCGKRAIGTVLVGATPVNVIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75T, L210W, T215Y | K219N | Y181C | V35K, T39A, S68G, V118I, K122KQ, I135V, S162A, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, K223Q, P243S, V245E, T286A, E291D, V292I, I293V, P294T, S322A, I326V |
| >71340| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICAELEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DQDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI CQYMDDLYVGSDLEIGQHRAKIKELREHLWKWGFYTPDNKHQQEPPFLWMGYELHPDKWT VQSIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |