<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-P ptPW12 U.S. 1995 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82F   L10I, T12S, I13V, I64V  
>ptPW12| 11 | codons 1-99 | clone 11
PQITLWQRPIVSVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF
>ptPW12| 10 | codons 1-99 | clone 10
PQITLWQRPIVSVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF
>ptPW12| 4 | codons 1-99 | clone 4
PQITLWQRPIVSVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF
>ptPW12| 3 | codons 1-99 | clone 3
PQITLWQRPIVSVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF
>ptPW12| 1 | codons 1-99 | clone 1
PQITLWQRPIVSVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF
>ptPW12| codons 1-99
PQITLWQRPIVSVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005