Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6406 | CA57767 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 48 |
| 2 | 3TC+AZT | 34 |
| 3 | 3TC+DDI | 5 |
| 4 | 3TC+DDI+RTV | 16 |
| 5 | D4T+DDC+NFV | 18 |
| 6 | D4T+DDC+NVP | 27 |
| 7 | 3TC+D4T+DDI+NFV+NVP | 15 |
| 8 | 3TC+AZT+NFV+NVP | 42 |
| 9 | 3TC+D4T+EFV+RTV+SQV | 3 |
| 10 | 3TC+D4T+RTV+SQV | 10 |
| 11 | 3TC+D4T+IDV+NFV | 74 |
| 12 | ABC+D4T+DDI | 3 |
| 13 | ABC+D4T+DDI+LPV | 22 |
| 14 | ABC+DDI+LPV+TDF | 7 |
| 15 | ABC+APV+DDI+LPV+TDF | 72 |
| 16 | 3TC+D4T+IDV+RTV+TDF | 130 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54A, V82A, L90M | K43T | L10I, I62V, L63P, I64V, A71AV, I72IV, V77I |
| >CA57767| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWTPKMIVGIGGFAKVRQYD QVPVEICGHKVVGTVLIGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, L210W, T215Y | V75S, K219E | K101E, Y181C, G190A | V108I | P4S, K20R, V35L, E44D, L109I, V118I, K122E, I135V, G196E, R211K, D218E, L228H, Q242H, S251IV, A272S, L283I, I293V | V179Y |
| >CA57768| codons 1-300 PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTRWRKISDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTIIDVGDAYFSIPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIYI CQYVDDLYVASDLEIEQHRTKIEELRQHLWKWGFYTPEEKHQKEPPFHWMGYELHPDKWT VHPIVLPEKDVWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLIRGTKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |