Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA2205 | CA57677 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T | 56 |
| 2 | 3TC+D4T+EFV+NFV | 13 |
| 3 | 3TC+D4T+EFV | 217 |
| 4 | 3TC+AZT | 69 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36L, N37A, I62V, L63P, I64V, I72V |
| >CA57677| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEELALPGRWKPKMIGGIGGFIKVRQYD QVPVEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V | Y188L | V179D | K20KR, V35M, T39A, K102M, K103R, K122E, D123DN, I135T, Q174K, D177E, I202V, F214FL, V245M, A272S, L283I, T286A, A288S, I293V, E312K, D324E, Q334E, R356K, G359S, K390R, V435I, L469I, T470N, H483Y, Q507H, Q524E, V531I, A554S, K558R |
| >CA57678| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKMRKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPEIDI YQYVDDLLVGSDLEIGQHRTKVEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLIRGAKSLTEVVPLTEEAE LELAENREILKKPVHGVYYDPSKELIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSINDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIHAQPDKSESELVSQIIEELIKKEKIYLAWVPAHK GIGGNEQVDKLVSSGIRRVL |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |