Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1467 | CA57664 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 69 |
| 2 | 3TC+AZT+IDV | 52 |
| 3 | D4T+DDC+NFV | 74 |
| 4 | 3TC+ABC+EFV+RTV+SQV | 57 |
| 5 | Unknown | 270 |
| 6 | LPV+NVP+SQV+TDF | 13 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, Q151M, L210W, T215Y | A62V, V75I, F116Y | K103N, M230L | V108I | R83K, D123E, K166R, D177E, I202V, A272P, I293V, E297K |
| >CA57664| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FVIKKKNSDKWRKLIDFRELNKKTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYYSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTRILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLWRWGFYTPDKKHQKEPPFLWLGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33F, F53L | L10IV, K20R, E35D, M36I, R41K, L63P, A71V, I93L |
| >CA57663| codons 1-99 PQITLWQRPVVTIKIGGQLREALLDTGADDTVFEDINLPGKWKPKLIGGIGGLVKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |