Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1169 | CA57651 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 226 |
| 2 | AZT+DDC | 35 |
| 3 | 3TC+AZT | 44 |
| 4 | 3TC+AZT+SQV | 22 |
| 5 | 3TC+AZT+NVP | 17 |
| 6 | 3TC+D4T+NFV | 15 |
| 7 | 3TC+D4T+RTV+SQV | 37 |
| 8 | 3TC+D4T | 36 |
| 9 | 3TC+D4T+IDV | 225 |
| 10 | Unknown | 112 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | K43T, G73S | L10IV, K20R, E35D, M36I, N37ND, Q61QR, I62V, L63P, A71V, I72EK, I93L, C95F |
| >CA57651| codons 1-99 PQITLWQRPVVTIKIGGQLREALLDTGADDTVLEDIDLPGRWTPKIIGGIGGFVKVRQYD RVPIEICGHKVKSTVLVGPTPANIIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, V75M, M184V, L210W | D67G, F77L, T215H | T39X, K43KQ, E44D, A98S, K101Q, V111I, V118I, K122E, A158S, S162SDGN, I202IV, T286A, I293V, E297K |
| >CA57652| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICXELEQDGKISKIGPENPYNTPV FAIKKKGSDKWRKLMDLRELNKRTQDFWEVQLGIPHPSGLQKKKSVTVLDIGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQNSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKVEELRQHLWRWGFHTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTKEAE L |
References
| Author | Title | Citation |
| Rhee, SY | Genotypic predictors of human immunodeficiency virus type 1 drug resistance. | PNAS, 2006 |