Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7848 | CA57650 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 230 |
| 2 | AZT+DDI | 9 |
| 3 | 3TC+D4T | 90 |
| 4 | D4T+DDI+NFV | 132 |
| 5 | 3TC+ABC+APV | 65 |
| 6 | LPV+NVP+TDF | 113 |
| 7 | 3TC+TDF | 82 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, M184V, L210W, T215Y | D67G, V75L, K219R | V106A | V108I, F227L | E44D, V60I, V118I, K122E, D123E, I135T, I142V, Q174QR, I195IV, G196E, E203K, Q207E, H208Y, R211K, K223E, V245K, A272P, E297EK |
| >CA57650| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPI FAIKKKGSDKWRKLLDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATILDVGDAYFSIPL DEEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDIVI YQYVDDLYVGSDLEVEQHRTKIKELREYLWKWGFYTPDRKHQEEPPLLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, M36MI, I64V, C67W |
| >CA57649| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QILVEIWGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |