Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4900 | CA57629 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 126 |
| 2 | 3TC+AZT | 100 |
| 3 | 3TC+AZT+IDV | 56 |
| 4 | D4T+DDI+EFV | 39 |
| 5 | ABC+APV+D4T+DDI | 284 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, V82A | L10F | L33V, R41K, Q61QH, L63P |
| >CA57629| codons 1-99 PQITLWQRPFVTIKIGGQLKEALLDTGADDTVVEEMNLPGKWKPKMIGGIGGFMKVRQYD HIPIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215F | K219Q | V60I, K122E, D123S, I135V, K166R, D177E, T200I, E203D, R211K, F214L, D218E, L228H, V245M, A272P |
| >CA57630| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRIKIDELRQHLLKWGLFTPEQKHQKEPPFHWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |