Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH7056 | ESH7056 | Malawi | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | NA |
| 2 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I15V, L19I, M36I, R41K, H69K, L89M, I93L | K20G |
| >ESH7056| codons 1-99 PQITLWQRPVVTIKVGGQIGEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, E40D, K43KR, S48T, D121Y, K122E, I159V, K173AT, Q174K, D177E, Q197P, T200A, Q207E, R211K, V245Q, A272AP, K277KR, T286A, E291D, V292I, V317A |
| >ESH7056| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEREGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAVFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGPHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Eshleman, SH | Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP. | J Infect Dis, 2005 |