Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH7040 | ESH7040 | Malawi | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | NA |
| 2 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, T12S, K14KR, L19I, M36MI, R41K, D60E, H69K, L89M, I93L |
| >ESH7040| codons 1-99 PQITLWQRPVVSIRIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN, Y188YC | P4S, V35T, E36A, T39D, S48T, K122E, D123G, I142IV, S162A, K173T, Q174K, D177E, T200A, Q207E, R211RK, V245Q, E248D, A272P, Q278H, T286TA, E291D, I293V |
| >ESH7040| codons 1-335 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI YQYMDDLCVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Eshleman, SH | Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP. | J Infect Dis, 2005 |