<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ESH9028 ESH9028 Malawi 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP NA
2 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35D, M36L, R41K, R57K, D60E, Q61N, H69K, K70KR, V77VI, L89M, I93L  
>ESH9028| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDLNLPGKWKPKMIGGIGGFIKVKQYE
NILIEICGKRAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36Q, T39E, S48T, K122E, D123N, I135T, K166R, K173T, Q174R, T200A, I202V, Q207E, F214L, V245L, A272P, K277R, T286A, E291D, V292I, I293V  
>ESH9028| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTQICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTRNPDIVI
YQYMDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Eshleman, SH Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP. J Infect Dis, 2005