Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH9028 | ESH9028 | Malawi | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | NA |
| 2 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36L, R41K, R57K, D60E, Q61N, H69K, K70KR, V77VI, L89M, I93L |
| >ESH9028| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDLNLPGKWKPKMIGGIGGFIKVKQYE NILIEICGKRAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36Q, T39E, S48T, K122E, D123N, I135T, K166R, K173T, Q174R, T200A, I202V, Q207E, F214L, V245L, A272P, K277R, T286A, E291D, V292I, I293V |
| >ESH9028| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTQICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTRNPDIVI YQYMDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Eshleman, SH | Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP. | J Infect Dis, 2005 |