Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-S | ptSW12 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 12 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, V82A | I15V, N37D, L63P, Q92R, I93L |
| >ptSW12| 7 | codons 1-99 | clone 7 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLTRIGCTLNF >ptSW12| 6 | codons 1-99 | clone 6 PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >ptSW12| 5 | codons 1-92 | clone 5 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQ >ptSW12| 4 | codons 1-99 | clone 4 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLARIGCTLNF >ptSW12| 3 | codons 1-99 | clone 3 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLTRIGCTLNF >ptSW12| 2 | codons 1-99 | clone 2 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptSW12| 1 | codons 1-99 | clone 1 PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >ptSW12| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTILEEMDLPGRWKPKIVGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLTRLGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |