Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9053 | 9053_d1 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI+ NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | I62V, I64V |
| >9053_d1| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QVLVEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67HN, K70KR, M184V, T215FV | K219E | K20KR, T69TN, W88C, V118VI, A158S, S162D, K166R, E169D, R211K, F214L, V245M, E297K |
| >9053_d1| codons 1-311 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKHSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQDSMTRILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLFTPDEKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILK |
References
| Author | Title | Citation |
| Mo, H | Selection of resistance in protease inhibitor-experienced, human immunodeficiency virus type 1-infected subjects failing lopinavir- and ritonavir-based therapy: mutation patterns and baseline correlates. | J Virol, 2005 |