Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI+ NRTI | NA |
| 2 | LPV+ NVP+ NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54S, V82A | L10I, E34Q, I62V, L63P, A71V, I72V, T74S, V77I, I93L |
| >9124_d59| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLQEMNLPGRWKPKMIVGIGGFSKVRQYD QVPIEICGHKVVGSVLIGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, Q151M, M184V | V75I, F77L, F116Y, T215V, K219Q | Y181YC, G190GA | K20R, K32KE, K49KR, T69N, K101KQ, S162D, K166R, G196E, I202V, Q207E, R211RK, H221HY, A272P, A288AS |
| >9124_d59| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSNRWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQDSMTRILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKVEELREHLLRWGFVTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE |
References
| Author | Title | Citation |
| Mo, H | Selection of resistance in protease inhibitor-experienced, human immunodeficiency virus type 1-infected subjects failing lopinavir- and ritonavir-based therapy: mutation patterns and baseline correlates. | J Virol, 2005 |