Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| WJ_pat7728 | 7728_W0 | U.S. | 2002 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I15V, L19I, R41K, D60E, Q61E, L63V, H69Q, V77I |
| >7728_W0| codons 1-99 PQITLWQRPIVTIKVGGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE EIVIEICGQKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K64R, D123E, I135T, S162C, T200A, V245M, T286A, T296S, E297K | V21VD |
| >7728_W0| codons 1-297 PISPIETVPVKLKPGMDGPKDKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLSK |
References
| Author | Title | Citation |
| Weber, J | Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation. | J Clin Microbiol, 2005 |