Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| WJ_pat7101 | 7101_W24 | U.S. | 2002 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | TDF+ 3TC+ EFV | 23 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, M184V | A62AV | V106M | V179D | E6D, S68SN, D123E, I178L, E194EK, G196E, T200I, R211RK, F214L, V245T, K249Q, K275R, V276I, I293V, P294Q | V21VD |
| >7101_W24| codons 1-297 PISPIDTVPVKLKPGMDGPKDKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKRKDNTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLDI YQYVDDLYVGSDLKIEQHRIKIEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEQDSWTVNDIQKLVGKLNWASQIYAGIRIKQLCKLLRGTKALTEVVQLTE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37S, R41K, L63P, I72V, V77VI |
| >7101_W24| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation. | J Clin Microbiol, 2005 |