Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA23800 | CA55226 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 22 |
| 2 | 3TC+AZT+IDV | 78 |
| 3 | 3TC+D4T+NFV | 96 |
| 4 | ABC+APV+EFV+RTV | 52 |
| 5 | 3TC+ABC+AZT+LPV | 13 |
| 6 | 3TC+ABC+AZT | 85 |
| 7 | 3TC+ABC+AZT+EFV | 24 |
| 8 | 3TC+AZT+EFV+TDF | 57 |
| 9 | ATV+D4T+RTV+TDF | 23 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219E | L100I, K103N | V90I, D123E, S162D, D177E, Q207E, R211K, L228HR, A272P, K277R, L283I, R284K, I293V, E297K |
| >CA55226| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFFTPDEKHQKEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIKGTKALTEVVPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I50L, V82T, L90M | L10R, N37H, R41K, L63P, A71I, I72V, V77I, I93L |
| >CA55225| codons 1-99 PQITLWQRPRVTIKIGGQLKEALLDTGADDTILEEMHLPGKWKPKIVGGLGGFIKVRQYD QIPIEICGHKIVGTVLIGPTPTNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |