Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1329 | CA55164 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ IDV | 21 |
| 2 | 3TC+ D4T+ NFV | 57 |
| 3 | SQV+ 3TC+ AZT+ RTV | 41 |
| 4 | 3TC+ AZT+ EFV+ SQV | 20 |
| 5 | Unknown | 286 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V | K103N | P225H | V35R, T39A, K102Q, D123E, I135T, I142V, S162C, T200A, V245T, A272P, I293V, E297K |
| >CA55164| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICAELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEHPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I84V, L90M | L10F, L33F, K43T, N88D | I15V, E35D, M36L, N37E, D60E, I62V, L63P, I93L |
| >CA55163| codons 1-99 PQITLWQRPFVTIKVGGQLKEALLDTGADNTVFEDLELPGRWTPKMIGGIGGFIKVRQYE QVPIEICGHKAIGTVLVGPTPVNVIGRDLMTQLGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |