Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9956 | CA55121 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 13 |
| 2 | DDI | 30 |
| 3 | 3TC+D4T | 48 |
| 4 | 3TC+D4T+DDC+NFV | 13 |
| 5 | 3TC+AZT+NVP | 13 |
| 6 | 3TC+AZT+SQV | 204 |
| 7 | 3TC+AZT+LPV+NVP | 160 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54T, V82A, L90M | L10V, L19I, K20R, E35D, M36I, N37D, R41K, L63P, I64V, A71V, I93L |
| >CA55121| codons 1-99 PQITLWQRPVVTIKIGGQIREALLDTGADDTVLEDIDLPGKWKPKMIVGIGGFTKVRQYD QIPVEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | P4S, E28G, S48ST, K122P, I135L, R211K, F214L, A272P, V276I, K277R, T286A, P294Q, E297K |
| >CA55122| codons 1-300 PISSIETVPVKLKPGMDGPKVKQWPLTGEKIKALVEICTEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTEVIQLTKEAE |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, V31I, V37I, A91T, L101I, S119P, V201I, I204L, S230N, L234F, A265V | D25DGV |
| >CA124193| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMASVFNLPPIVAKEIIASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPTETGQETAYFILKLAGRWPVKTIHTDNGPN FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDILATDIQTKELQKQITKIQNFRVYYRDNRDPFWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |