Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA790 | CA55114 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 365 |
| 2 | AZT+DDC | 22 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+AZT+IDV | 9 |
| 5 | 3TC+D4T+IDV | 60 |
| 6 | D4T+DDI+RTV+SQV | 58 |
| 7 | D4T+DDI+EFV+RTV+SQV | 28 |
| 8 | D4T+DDI+EFV+SQV | 18 |
| 9 | Unknown | 292 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, L74V, M184V, T215Y | K219Q | K101EQ, Y181C, G190S | V35I, T39A, K49R, V106VI, K122E, D123E, I135T, R172RK, V179IT, D218E, D237E, E248D, A272AP, A288AT, I293IV, E297A |
| >CA55114| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISRIGPENPYNTPV FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSITVLDVGDAYFSVPL DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDITI CQYVDDLYVSSDLEIGQHRTKIEELRQHLLRWGFYTPEQKHQKEPPFLWMGYELHPEKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKTLTEVVPLTAEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V | L10F, L24I, L33F, G73T | I13V, G16A, L19LI, L63P, I66V, I72V, P79D, I93L |
| >CA55113| codons 1-99 PQITLWQRPFVTVKIAGQIKEALIDTGADDTVFEEMNLPGRWKPKIIGGIGGFVKVRQYD QIPIEVCGHKAVTTVLVGDTPVNVIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |