Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7916 | CA55062 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 57 |
| 2 | 3TC+D4T | 9 |
| 3 | 3TC+AZT+IDV | 65 |
| 4 | 3TC+D4T+NFV | 174 |
| 5 | 3TC+AZT+NVP | 210 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, K70KR, M184V, T215F | K219KE | G190A | A98G | E6EK, T39AE, I94IL, K102KQ, K122E, D123E, I135L, I142V, S162A, D177E, V179I, V245T, A272P, I293V, E297A |
| >CA55062| codons 1-300 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICEELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGLPHPGGLKQKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSLNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEIII YQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTAEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10V, E35D, M36V, L63P, A71V, I93L |
| >CA55061| codons 1-99 PQITLWQRPVVTIKIGGQLKEALLDTGADNTVLEDVNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |