Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG320_3671 | 3671 | U.S. | 1996 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 325 |
| 2 | None | 16 |
| 3 | DDI | 13 |
| 4 | None | 55 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L210LW | T215D | K103N | Y318F | K20R, V35VI, K122E, I135T, S162C, E203D, R211K, E224ED, A272P, K277R, L283I, I293V, Q334DE, R356K, G359S, A371AV, T377MV, K390R, A400T, T403A, K451R, L452S, S468P |
| >3671| codons 1-489 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIDELRQHLWKWGFDTPDKKHQKDPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVVPLTEEAE LELAENREILKEPVHGVFYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEVVQKIAVESIVIWGKTPKFRLPIQKETWETWWAEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETRSGKAGYVTDRGRQKVVPLTDTTNQKTELQ AIHLALQDS |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, N37P, L63P, I72IV |
| >3671| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMPLPGRWKPKMIGGIGGFIKVRQYDQIP IEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Hammer, SM | A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. | N Engl J Med, 1997 |