<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ACTG320_3671 3671 U.S. 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 325
2 None 16
3 AZT+DDI+DLV 13
4 None 55

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L210LW T215D K103N Y318F K20R, V35VI, K122E, I135T, S162C, E203D, R211K, E224ED, A272P, K277R, L283I, I293V, Q334DE, R356K, G359S, A371AV, T377MV, K390R, A400T, T403A, K451R, L452S, S468P  
>3671| codons 1-489
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIDELRQHLWKWGFDTPDKKHQKDPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVFYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKIAVESIVIWGKTPKFRLPIQKETWETWWAEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETRSGKAGYVTDRGRQKVVPLTDTTNQKTELQ
AIHLALQDS

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, N37P, L63P, I72IV  
>3671| codons 4-99
TLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMPLPGRWKPKMIGGIGGFIKVRQYDQIP
IEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Hammer, SM A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med, 1997