Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG320_3611 | 3611 | U.S. | 1996 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 4 |
| 2 | None | 63 |
| 3 | AZT | 130 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19I, K20R, L33V, M36L, R41K, Q61H, I64IV, E65ED, V82VI, L89LM, I93ILM |
| >3611| codons 1-99 PQITLWQRPLVTIKIGGQIREALLDTGADDTVVEELNLPGKWKPKMIGGIGGFIKVRQYD HILVDICGHKAIGTVLVGPTPINIIGRNMLTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, T27TP, S68SN, K102KR, G196GE, Q207T, V245T, E248DN, I293V, K311R, I326V, G333E, Q334H, R356RK, M357MI, R358RK, T377R, T386I, A400T, Y405YH, K431T, V435VA, V466A, H483Y, D488X | L210ST |
| >3611| codons 1-488 PISPIDTVPVKLKPGMDGPKVKQWPLPEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDNTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRTKIEELRTHLTRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPNKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILREPVHGVYYDPSKDLVAEIQKQEHGQWTYQIYQEPFKNLKTGKYAKIKGA HTNDVKQLTEAVQKIARESIVIWGKIPKFKLPIQKETWETWWTEHWQATWIPEWEFVNTP PLVKLWYQLETEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKAVSLTDTTNQKTELQ AIYLALQE |
References
| Author | Title | Citation |
| Hammer, SM | A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. | N Engl J Med, 1997 |