Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG320_2797 | 2797 | U.S. | 1996 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 256 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | K219Q | K20R, T69N, V118I, I135T, E138A, K166KR, R211K, F214L, P243T, K277R, T286A, E291D, P294ST, E297K, Q334E, T369TA, A376T, K390R, A400T, T403A, L452LI, D460N, S468A, L469I, H483Y |
| >2797| codons 1-490 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGLYTPDQKHQKEPPFLWMGYELHPDKWT VQTIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDVITLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLAEAVQKITTESIVIWGKTPKFRLPIQKETWETWWAEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKIGKAGYVTNRGRQKVVAITDTTNQKTELQ AIYLALQDSG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L63S, I64V |
| >2797| codons 1-99 PQITLWQRPLVSIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QISVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Hammer, SM | A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. | N Engl J Med, 1997 |