Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99UFRJ_9 | 99UFRJ_9 | Brazil | 1999 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ IDV | 87 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46L | E21K, E34K, E35N, M36I, R41K, R57K, Q61H, L89M |
| >99UFRJ_9| codons 1-99 PQITLWQRPLVTIKIGGQLKKALLDTGADNTVLKNINLPGKWKPKLIGGIGGFIKVKQYD HILIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K122E, D123E, T200A, Q207E, R211K, V245Q, A272P, K277R, K281R, I293V, E297K, R356K, G359S, I375V, A376T, S379C, V381I, K385R, K390R, T397I, A400T, V435I, V466T, S468P, D471E, T477A, H483Q, L491S, L517I, S519N, K527Q, V531I, A534S, V559I |
| >99UFRJ_9| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKVTTECIIIWGRTPKFRLPIQKEIWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKTVPLTETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIQKEKIYLSWVPAHK GIGGNEQVDKLVSAGIRKIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, L74I, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234V, D256E | S283G |
| >99UFRJ_9| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIIIVAVHVASGYIEAEVIPAETGQDTAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Thomson, MM | Analysis of near full-length genome sequences of HIV type 1 BF intersubtype recombinant viruses from Brazil reveals their independent origins and their lack of relationship to CRF12_BF. | ARHR, 2004 |