Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99UFRJ_1 | 99UFRJ_1 | Brazil | 2000 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T | 24 |
| 2 | 3TC+ D4T+ NVP+ NFV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, M36I, R41K, R57K, D60E, Q61D, V77I, L89M |
| >99UFRJ_1| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE DILIEICGHKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106A | K49R, D123E, R211K, E248V, A272P, I293V, I329L, F346Y, M357A, Q394L, A400T, E404D, E413D, K431T, V435A, A446S, L452K, R461K, V466A, V467I, D471E, K476R, T477A, H483Q, L491S, L517I, S519N, K530KR, A534S, E546K, V559I |
| >99UFRJ_1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPVKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPYKNLKTGKYARARGA HTNDVKQLTEAVQKIATESIVIWGKTPKFKLPILKETWETWWTDYWQATWIPDWEFVNTP PLVKLWYQLETEPIAGAETFYVDGASNRETKKGKAGYVTDKGRQKAISLTETTNQRAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKERVYLSWVPAHK GIGGNKQVDKLVSAGIRKIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, E13K, S17N, V31I, I72V, I84L, L101I, S119P, T122I, T125A, K136Q, K156N, V165I, V201I, A205S, K211R, T218S, L234V, D256E | S283G |
| >99UFRJ_1| codons 1-288 FLDGIDKAQEDHKKYHNNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGPN FISTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNNELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISTDIQTRELQKQISKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Thomson, MM | Analysis of near full-length genome sequences of HIV type 1 BF intersubtype recombinant viruses from Brazil reveals their independent origins and their lack of relationship to CRF12_BF. | ARHR, 2004 |