Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 208 | 208 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 64 |
| 2 | 3TC+ AZT | 20 |
| 3 | 3TC+ D4T+ NFV | 67 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46I | N88D | L10I, N37S, R41K, L63P, K70R, V77I |
| >208| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADNTVLEEMSLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGHRAIGTVLIGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Y115F, Q151M | V75I, F77L, F116Y, K219E | S68G, D177E |
| >208| codons 36-225 EICTEMEKEGKISKIGPENPYNTPVFAIKRKDGTRWRKLIDLRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAFYSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKG SPAIFQSSMTKILEPFRKQNPEIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFT TPDEKHQKEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |