Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 274 | 274 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 74 |
| 2 | 3TC+ AZT | 10 |
| 3 | 3TC+ AZT+ RTV | 37 |
| 4 | 3TC+ D4T+ NVP+ RTV+ SQV | 125 |
| 5 | 3TC+ D4T+ EFV+ NFV | 68 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, L210W, T215Y | K219N | Y181C, G190A | T39A, E44D, K102Q, V118I, K122E, R125K, I135T, I142V, S162C, D177E, V179I, T200A, E203K, H208Y, R211K, K223E |
| >274| codons 36-225 EICAELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIP HPAGLKQKKSVTVLDVGDAYFSIPLDEDFKKYTAFTIPSTNNETPGVRYQYNVLPQGWKG SPAIFQCSMTKILEPFRKQNPEIIICQYVDDLYVASDLEIGQHRAKIKELRQYLWKWGFY TPDNKHQEEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |