Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 198 | 198 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 168 |
| 2 | 3TC+ AZT | 32 |
| 3 | 3TC+ D4T+ RTV | 29 |
| 4 | 3TC+ D4T+ NFV | 73 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75M, M184V, L210W, T215Y | K101Q, V118I, K122E |
| >198| codons 36-225 EICTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLMDFRELNKRTQDFWEVQLGIP HPAGLQKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLWRWGFY TPDKKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | E35D, M36I, N37D, R57K, L63P, I64V |
| >198| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADNTVLEDIDLPGRWKPKMIGGIGGFIKVKQYD QIPVEICGHKAIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |