Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 197 | 197 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 46 |
| 2 | 3TC+ D4T | 60 |
| 3 | 3TC+ D4T+ RTV+ SQV | 65 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62V, V75I, F77L, F116Y, K219Q | E138K | K49R, I50V, S68G, K101Q, R172K, V179A, I202V, F214L |
| >197| codons 36-225 EICTEMEKEGKISRVGPENPYNTPVFVIKKKDGTKWRKLIDLRELNKRTQDFWEVQLGIP HPAGLQKKKSVTVLDVGDAYYSVPLDKDFRKYTAFTIPSINNKTPGIRYQYNVLPMGWKG SPAIFQSSMTKILEPFKKQNPDIAIYQYVDDLYVGSDLEIGQHRTKVEELRQHLLRWGLT TPDQKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37S, L63C, I64V, V77I |
| >197| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QICVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |