Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 265 | 265 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 87 |
| 2 | 3TC+ AZT+ NFV | 60 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219E | D123E, A158S, K173Q, Q174R, F214L |
| >265| codons 36-225 EICTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG SPSIFQSSMTKILEPFRQRNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLF TPDEKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10I, E35D, N37H, R41K, L63P, V77I |
| >265| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADNTVLEDMHLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |