Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 253 | 253 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 97 |
| 2 | 3TC+ AZT+ D4T+ RTV | 22 |
| 3 | 3TC+ D4T+ RTV | 185 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | K43Q, S68G, V118I, I135T, D177E, R211K, F214L |
| >253| codons 36-225 EICTELEQEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLF TPDKKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L10V, G17D, K20R, E35D, M36I, R41K, D60E, I62V, L63P |
| >253| codons 1-99 PQITLWQRPVVTIKIGDQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYE QVPIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |