Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 248 | 248 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ NFV | 69 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | K20I, N37S, L63P, V77I |
| >248| codons 1-99 PQITLWQRPLVTIKIGGQLIEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | V90I, V189I, Q197P |
| >248| codons 36-225 EICTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYIGSDLEIGPHRTKIEELRQHLLRWGFY TPDKKHQKEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |