<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
242 242 Brazil 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDI 35
2 3TC+ AZT+ DDI 13
3 3TC+ AZT 85
4 3TC+ D4T+ NFV 177

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, M46I N88D L10V, I13V, R41K, R57K, D60E, Q61D, I64V, V77I, I85V  
>242| codons 1-99
PQITLWQRPVVTVKIGGQLKEALLDTGADNTVLEEMNLPGKWKPKIIGGIGGFIKVKQYE
DILVEICGHKAIGTVLIGPTPVNIVGRDLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        D123E, I135V, S162C, D177E, I178V  
>242| codons 36-225
EICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP
HPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKG
SPAIFQCSMTKILEPFRKQNPEVVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFT
TPDKKHQKEP

References
Author Title Citation
Dumans, AT Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. J Infect Dis, 2004