<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
169 169 Brazil 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+DDI 63
2 3TC+AZT+RTV 145

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54IV, V82S, I84V L33F I62V, L63P, A71V, V77I  
>169| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFVKVRQYD
QVPIEICGHKVIGTVLIGPTPSNVIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y       K102Q, I142V, K166R, I178L, E204K, Q207E  
>169| codons 36-225
EICTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP
HPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKG
SPAIFQSSMTRILEPFRKQNPDLVIYQYVDDLYVGSDLEIGQHRTKIEKLREHLWRWGFY
TPDKKHQKEP

References
Author Title Citation
Dumans, AT Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. J Infect Dis, 2004