Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 238 | 238 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 132 |
| 2 | 3TC+ AZT+ NFV | 34 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46I | L63P, E65D, I72V |
| >238| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QIPIDICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, V75M, M184V, L210W, T215Y | V60I, K122P, I135T, I142V, K166R, D177E, T200I, R211K |
| >238| codons 36-225 EICTEMEKEGKISKIGPENPYNTPIFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKG SPAIFQSSMTRILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRIKIEELRQHLWKWGFY TPDKKHQKEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |