Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 237 | 237 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 7 |
| 2 | 3TC+AZT | 50 |
| 3 | 3TC+AZT+RTV+SQV | 9 |
| 4 | 3TC+AZT+NFV+SQV | 115 |
| 5 | 3TC+AZT+RTV+SQV | 13 |
| 6 | AZT+DDI | 31 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, L210W, T215Y | A98G | K43N, E44D, K82R, K122E, D123E, I167V, D177E, H208Y, R211K, D218E |
| >237| codons 36-225 EICTELENDGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNRRTQDFWEVQLGIP HPGGLKKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG SPAIFQSSMTKVLEPFRKQNPEIVIYQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGFY TPEKKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, N37S, R41K, D60E, L63P, I93L |
| >237| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYE QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |