Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 233 | 233 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 91 |
| 2 | 3TC+ AZT | 42 |
| 3 | 3TC+ AZT+ RTV | 13 |
| 4 | 3TC+ D4T+ NFV+ NVP | 131 |
| 5 | 3TC+ APV+ AZT+ EFV | 38 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K101E, Y181V, G190A | A98G, V108I | K43Q, E44D, V118I, D123E, I135T, E203K, Q207E, H208Y, R211K, K223Q |
| >233| codons 36-225 EICTELEQDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIP HPGGLEKKKSVTILDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVIVQYVDDLYVASDLEIGQHRTKIKELREYLWKWGFY TPDKKHQQEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | T12P, I13V, I15V, K20T, M36I, N37T, L63P, H69K, A71I, I93L |
| >233| codons 1-99 PQITLWQRPLVPVKVGGQLTEALLDTGADDTVLEEITLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGKKIIGTVLVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |