Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 230 | 230 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 16 |
| 2 | 3TC+AZT | 97 |
| 3 | 3TC+D4T+NFV | 168 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I15V, G17E, K20T, E35D, M36I, K45R, R57K, D60E, Q61D, L63P |
| >230| codons 1-99 PQITLWQRPLVTIKVGEQLTEALLDTGADNTVLEDINLPGRWKPRMIGGIGGFIKVKQYE DIPIEICGHKAIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | K43R, K122E, D123S, I135T, D177E, T200A, R211T |
| >230| codons 36-225 EICTEMEREGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLTWGFY TPDKKHQKEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |