Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 227 | 227 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 13 |
| 2 | AZT+ DDI | 148 |
| 3 | 3TC+ AZT | 45 |
| 4 | 3TC+ AZT+ NFV | 113 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10I, I13V, I62V, L63P, I66F, A71T, V77I |
| >227| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEFCGHKTIGTVLIGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W | A98G | E44D, K102Q, V118I, K122X, I135T, G196E, E203D, H208Y, R211K |
| >227| codons 36-225 EICTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIP HPGGLKQKKSVTVLDVGDAYFSIPLDXDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRTKIDELRQYLWKWGFT TPDKKHQKEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |